Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844110 | 0.91 | MAOA (0.40) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL3551960 | 0.87 | BRD4 (0.39) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL17844119 | 0.85 | TAAR1 (0.40) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL17844227 | 0.84 | POLB (0.39) | MEN1KMT2APOLBMAPTHPGD | |
| SCHEMBL5184298 | 0.80 | CA12 (0.33) | MEN1KMT2AMAPTHPGDLMNA | |
| SCHEMBL17844175 | 0.78 | CA12 (0.38) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL17844244 | 0.77 | MTNR1A (0.40) | GAAHPGDLMNAATMNPSR1 | |
| SCHEMBL17844236 | 0.77 | DRD2 (0.44) | MEN1KMT2APOLBGAALMNA | |
| SCHEMBL17844198 | 0.77 | MEN1 (0.48) | MEN1KMT2ACTDSP1POLBGAA | |
| SCHEMBL17844148 | 0.76 | KMT2A (0.40) | MEN1KMT2AGAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |