Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | PDE6A | P16499 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844168 | 0.87 | MAPK1 (0.37) | ADORA2BPDE4BPDE7AMAPK14ALDH1A1 | |
| SCHEMBL17844251 | 0.86 | FAAH (0.39) | ADORA2BPDE4BPDE7AALDH1A1 | |
| SCHEMBL5199815 | 0.85 | ADORA2B (0.35) | ADORA2BCYP2C9SMN1; SMN2KAT2BALDH1A1 | |
| SCHEMBL17844225 | 0.77 | MAPK10 (0.42) | ADORA2BPDE4BPDE7AFYNL3MBTL1 | |
| SCHEMBL17844241 | 0.77 | MAPK10 (0.42) | ADORA2BPDE4BPDE7AFYNL3MBTL1 | |
| SCHEMBL17844144 | 0.74 | FAAH (0.40) | ADORA2BCYP2C9SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL2004915 | 0.70 | BRD4 (0.37) | CYP2C9SMN1; SMN2MAPK14PDE5APDE6A | |
| SCHEMBL17844132 | 0.69 | FAAH (0.39) | ADORA2BKAT2BALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL3503724 | 0.68 | MAPT (0.45) | CYP2C9SMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5186704 | 0.67 | FAAH (0.38) | ADORA2BSMN1; SMN2PDE4BPDE7APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |