Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MERTK | Q12866 | 6/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 5/20 | 0.36 |
| ▸ | FLT3 | P36888 | 4/20 | 0.36 |
| ▸ | GAS6 | Q14393 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844156 | 0.86 | ADORA2B (0.36) | PDE4BPDE7AALDH1A1ADORA2B | |
| SCHEMBL17844161 | 0.78 | FAAH (0.44) | FAAHMGLLALDH1A1KDM4EMAPT | |
| SCHEMBL17844241 | 0.77 | MAPK10 (0.42) | PDE4BPDE7AMAPTMEN1KMT2A | |
| SCHEMBL5184388 | 0.77 | FAAH (0.47) | FAAHMGLLALDH1A1KDM4EMAPT | |
| SCHEMBL5186011 | 0.75 | ALDH1A1 (0.48) | FAAHMGLLPDE4BALDH1A1CNR2 | |
| SCHEMBL17844174 | 0.74 | FAAH (0.40) | FAAHMGLLALDH1A1KDM4EMAPT | |
| SCHEMBL5320278 | 0.73 | ALDH1A1 (0.49) | FAAHMGLLALDH1A1KDM4EMAPT | |
| SCHEMBL17844168 | 0.73 | MAPK1 (0.37) | PDE4BPDE7AALDH1A1POLBADORA2B | |
| SCHEMBL17844198 | 0.73 | MEN1 (0.48) | FAAHMGLLALDH1A1MAPTMEN1 | |
| SCHEMBL17844070 | 0.73 | FAAH (0.40) | FAAHMGLLALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |