Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844241 | 1.00 | MAPK10 (0.42) | MAPK10MAPK8MAPK9PDE4BPDE7A | |
| SCHEMBL17844147 | 0.85 | GBA1 (0.35) | MAPK8PDE4BPDE7ABRD4MEN1 | |
| SCHEMBL17844251 | 0.77 | FAAH (0.39) | PDE4BPDE7AADORA2BMEN1MAPT | |
| SCHEMBL17844156 | 0.77 | ADORA2B (0.36) | MAPK8PDE4BPDE7AADORA2BFYN | |
| SCHEMBL1997878 | 0.70 | MAPK8 (0.42) | MAPK10MAPK8MAPK9PDE4BPDE7A | |
| SCHEMBL1999233 | 0.70 | MAPK8 (0.42) | MAPK10MAPK8MAPK9PDE4BPDE7A | |
| SCHEMBL1997879 | 0.70 | MAPK8 (0.42) | MAPK10MAPK8MAPK9PDE4BPDE7A | |
| SCHEMBL17844153 | 0.68 | MAPK8 (0.41) | MAPK10MAPK8MAPK9MEN1MAPT | |
| SCHEMBL17844164 | 0.67 | KAT2B (0.38) | MAPK9MAPK7MAPK1 | |
| SCHEMBL17844146 | 0.67 | HTR1B (0.39) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |