Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844156 | 0.87 | ADORA2B (0.36) | MAPK14ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL5199815 | 0.85 | ADORA2B (0.35) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL17844144 | 0.74 | FAAH (0.40) | MAPK1ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL17844251 | 0.73 | FAAH (0.39) | ALDH1A1ADORA2BPDE4BPDE7APOLB | |
| SCHEMBL2001680 | 0.70 | MAPK1 (0.39) | MAPK1MAPK14ALDH1A1CYP1A2CASP1 | |
| SCHEMBL3503724 | 0.70 | MAPT (0.45) | MAPK1ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL17844132 | 0.69 | FAAH (0.39) | ALDH1A1HSD17B10ADORA2B | |
| SCHEMBL5186704 | 0.67 | FAAH (0.38) | ALDH1A1HSD17B10ADORA2BPDE4BPDE7A | |
| SCHEMBL17844164 | 0.65 | KAT2B (0.38) | MAPK1CYP1A2POLB | |
| SCHEMBL5185885 | 0.65 | LMNA (0.43) | MAPK1ALDH1A1CYP1A2HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |