Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 17/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844250 | 0.88 | KAT2B (0.41) | SLC6A7 | |
| SCHEMBL3546550 | 0.86 | LMNA (0.42) | GLSTRPV1 | |
| SCHEMBL17844145 | 0.85 | HRH3 (0.38) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL17844219 | 0.82 | CKS1B (0.38) | KCNH2 | |
| SCHEMBL17844164 | 0.81 | KAT2B (0.38) | — | |
| SCHEMBL5260026 | 0.81 | GPR119 (0.38) | KCNH2 | |
| SCHEMBL17844240 | 0.81 | CHRM4 (0.39) | KCNH2 | |
| SCHEMBL17844162 | 0.81 | HRH3 (0.41) | KCNH2 | |
| SCHEMBL17844177 | 0.80 | JAK2 (0.46) | TRPV1 | |
| SCHEMBL5184355 | 0.77 | BRD4 (0.36) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |