Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LCAT | P04180 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844177 | 0.87 | JAK2 (0.46) | KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL17844250 | 0.86 | KAT2B (0.41) | HRH3KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL5316660 | 0.82 | METAP1 (0.49) | CHRM4KDM4EMAPTCHRM1CHRM3 | |
| SCHEMBL17844240 | 0.81 | CHRM4 (0.39) | HRH3CHRM4LCATKCNH2 | |
| SCHEMBL17844172 | 0.81 | GLS (0.43) | KCNH2 | |
| SCHEMBL17844219 | 0.80 | CKS1B (0.38) | HRH3LCATKCNH2 | |
| SCHEMBL5260026 | 0.79 | GPR119 (0.38) | LCATKCNH2 | |
| SCHEMBL3546550 | 0.78 | LMNA (0.42) | KDM4ELCATALDH1A1 | |
| SCHEMBL17844164 | 0.78 | KAT2B (0.38) | — | |
| SCHEMBL17844145 | 0.78 | HRH3 (0.38) | HRH3KDM4EMAPTLCATALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |