Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | GLS | O94925 | 12/20 | 0.36 |
| ▸ | LCAT | P04180 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 2/20 | 0.34 |
| ▸ | SKP1 | P63208 | 2/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3546550 | 0.88 | LMNA (0.42) | GLSLCATCKS1BSKP1SKP2 | |
| SCHEMBL17844172 | 0.85 | GLS (0.43) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL17844250 | 0.83 | KAT2B (0.41) | HRH3CKS1BSKP1SKP2TP53 | |
| SCHEMBL17844219 | 0.82 | CKS1B (0.38) | HRH3LCATCKS1BSKP1SKP2 | |
| SCHEMBL5260026 | 0.81 | GPR119 (0.38) | LCATCKS1BSKP1SKP2 | |
| SCHEMBL17844240 | 0.81 | CHRM4 (0.39) | HRH3LCATCKS1BSKP1SKP2 | |
| SCHEMBL17844177 | 0.80 | JAK2 (0.46) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17844164 | 0.80 | KAT2B (0.38) | — | |
| SCHEMBL17844162 | 0.78 | HRH3 (0.41) | HRH3LCATKDM4EALDH1A1MAPT | |
| SCHEMBL17844237 | 0.76 | PTPN1 (0.41) | TP53MAPTOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |