Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 3/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184329 | 0.87 | TYMP (0.42) | ASPHKDM8KAT2BKDM6BKDM4C | |
| SCHEMBL17844133 | 0.85 | KDM6B (0.43) | ASPHKDM8HPGDKAT2BKDM6B | |
| SCHEMBL17844110 | 0.73 | MAOA (0.40) | ASPHKDM8KDM6BKDM4CMAOA | |
| SCHEMBL17844245 | 0.72 | CYP1A2 (0.42) | HPGDALOX15TDP1KDM4EMEN1 | |
| SCHEMBL17844150 | 0.71 | MKNK1 (0.45) | ALOX15TDP1F2MAOBALDH1A1 | |
| SCHEMBL17844216 | 0.71 | EPHX1 (0.40) | ASPHKDM8MAOAMAOBKDM4E | |
| SCHEMBL6423073 | 0.65 | HRH1 (0.63) | HPGDALOX15TDP1MAOAALDH1A1 | |
| SCHEMBL17844229 | 0.65 | MEN1 (0.48) | HPGDMAOAMAOBKDM4EMEN1 | |
| SCHEMBL5186011 | 0.64 | ALDH1A1 (0.48) | HPGDKAT2BMEN1KMT2AALDH1A1 | |
| SCHEMBL12040591 | 0.64 | HRH1 (0.67) | HPGDALOX15TDP1MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |