Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 2/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844163 | 0.85 | PDE9A (0.42) | CES2 | |
| SCHEMBL5184329 | 0.78 | TYMP (0.42) | MAOAMAOBASAH1KMT2AMEN1 | |
| SCHEMBL17844245 | 0.77 | CYP1A2 (0.42) | KMT2AMEN1KDM4E | |
| SCHEMBL17844110 | 0.76 | MAOA (0.40) | MAOAMAOBASAH1KMT2AMEN1 | |
| SCHEMBL17844195 | 0.71 | ASPH (0.41) | MAOAMAOBASAH1KMT2AMEN1 | |
| SCHEMBL17844229 | 0.67 | MEN1 (0.48) | MAOAMAOBKMT2AMEN1KDM4E | |
| SCHEMBL28511931 | 0.60 | SIGMAR1 (0.55) | KMT2A | |
| SCHEMBL23019750 | 0.60 | GRIN2B (0.69) | EPHX1KMT2AGRIN2B | |
| SCHEMBL21242573 | 0.60 | GRIN2B (0.69) | EPHX1KMT2AGRIN2B | |
| SCHEMBL23599404 | 0.60 | GRIN2B (0.69) | EPHX1KMT2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |