Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | ASPH | Q12797 | 2/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184329 | 0.93 | TYMP (0.42) | KDM6BKDM4CASPHKDM8ASAH1 | |
| SCHEMBL5224541 | 0.89 | GBA1 (0.44) | KDM6BKDM4CGSK3BASPHKDM8 | |
| SCHEMBL17844195 | 0.85 | ASPH (0.41) | KDM6BKDM4CASPHKDM8ASAH1 | |
| SCHEMBL17844110 | 0.75 | MAOA (0.40) | KDM6BKDM4CASPHKDM8ASAH1 | |
| SCHEMBL5197239 | 0.73 | GSK3B (0.43) | KDM6BKDM4CGSK3BMAOAMAOB | |
| SCHEMBL17844216 | 0.72 | EPHX1 (0.40) | GSK3BASPHKDM8ASAH1TYMP | |
| SCHEMBL2001043 | 0.70 | ASAH1 (0.41) | KDM6BKDM4CGSK3BASAH1TYMP | |
| SCHEMBL4023147 | 0.67 | MAPKAPK2 (0.67) | KDM6BKDM4CGSK3BASPHKDM8 | |
| SCHEMBL6191025 | 0.67 | KCNH3 (0.58) | KDM6BKDM4CHPGD | |
| SCHEMBL17844229 | 0.66 | MEN1 (0.48) | MAOAMAOBCASP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |