Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784844 | 1.00 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL8649495 | 0.77 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL700953 | 0.71 | ADORA3 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL701748 | 0.71 | ADORA3 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL700952 | 0.71 | ADORA3 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL776698 | 0.71 | CA1 (0.33) | — | |
| SCHEMBL145452 | 0.71 | CA1 (0.33) | — | |
| SCHEMBL14669110 | 0.71 | CA1 (0.33) | — | |
| SCHEMBL30655945 | 0.71 | CA1 (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL28986371 | 0.69 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124695-A1 | Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors | NOVARTIS AG (CH) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124695-A1 | Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors | MME, REN, AGTR1 | ALDH1A1 175/4885L3MBTL1 3761/4885TSHR 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.