Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17849555 | 0.89 | KEAP1 (0.62) | KMT2AMEN1TDP1KEAP1NFE2L2 | |
| SCHEMBL16187950 | 0.86 | MEN1 (0.58) | KMT2AMEN1GAARECQLHSP90AA1 | |
| SCHEMBL17849561 | 0.83 | KMT2A (0.59) | KMT2AMEN1TDP1KEAP1NFE2L2 | |
| SCHEMBL808090 | 0.79 | HKDC1 (0.61) | KMT2AMEN1GAATDP1KEAP1 | |
| SCHEMBL7573136 | 0.78 | KEAP1 (0.76) | KMT2AMEN1TDP1KEAP1NFE2L2 | |
| SCHEMBL13765236 | 0.74 | KEAP1 (0.86) | KMT2AMEN1TDP1KEAP1NFE2L2 | |
| SCHEMBL12407072 | 0.73 | MAPT (0.54) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL12972046 | 0.73 | SLC40A1 (0.74) | KMT2AMEN1TDP1MAPTALDH1A1 | |
| SCHEMBL13852947 | 0.72 | NPC1 (0.58) | KMT2AMEN1GAAKEAP1NFE2L2 | |
| SCHEMBL18600090 | 0.72 | NR3C1 (0.42) | KMT2AMEN1GAAKEAP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |