SCHEMBL808090

SCHEMBL808090

Cc1ccc(S(=O)(=O)Nc2cccc3ccc(O)cc23)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.61
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
TDP1 Q9NUW8 2/20 0.56
ALDH1A1 P00352 5/20 0.56
LMNA P02545 4/20 0.56
MAPT P10636 3/20 0.56
POLB P06746 2/20 0.56
USP2 O75604 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
NOD2 Q9HC29 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
KEAP1 Q14145 1/20 0.56
NFE2L2 Q16236 1/20 0.56
EP300 Q09472 1/20 0.56
KAT2B Q92831 1/20 0.56
KAT8 Q9H7Z6 1/20 0.56
CYTH2 Q99418 1/20 0.55
HTT P42858 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849555 0.89 KEAP1 (0.62) HKDC1KMT2AMEN1TDP1ALDH1A1
SCHEMBL16187950 0.86 MEN1 (0.58) HKDC1KMT2AMEN1ALDH1A1LMNA
SCHEMBL808375 0.86 HSD17B2 (0.64) HSP90AA1RECQL
SCHEMBL16187949 0.85 KMT2A (0.60) KMT2AMEN1TDP1ALDH1A1MAPT
SCHEMBL11414744 0.83 NFKBIA (0.56) KMT2AMEN1ALDH1A1MAPTCYTH2
SCHEMBL7573136 0.83 KEAP1 (0.76) HKDC1KMT2AMEN1TDP1ALDH1A1
SCHEMBL9351736 0.80 KEAP1 (0.65) KMT2AMEN1MAPTKEAP1EP300
SCHEMBL7537943 0.80 RECQL (0.76) HKDC1KMT2AMEN1ALDH1A1LMNA
SCHEMBL17849561 0.80 KMT2A (0.59) KMT2AMEN1TDP1ALDH1A1LMNA
SCHEMBL13765236 0.79 KEAP1 (0.86) KMT2AMEN1TDP1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3056198-A2 USE OF COMPOUNDS FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS TO CHONDROCYTES MSP Co., Ltd (KR) 2016-08-17 EP claimed
EP-2617415-B1 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION (KR) 2016-04-20 EP claimed
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells MSP CO., LTD. (KR) 2015-09-10 US claimed
US-9068166-B2 Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2015-06-30 US claimed
US-20130236969-A1 Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2013-09-12 US claimed
EP-2617415-A2 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS Industry-Academic Cooperation Foundation, Yonsei University (KR) 2013-07-24 EP claimed
EP-3056198-A2 USE OF COMPOUNDS FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS TO CHONDROCYTES MSP Co., Ltd (KR) 2016-08-17 EP disclosed
US-9371286-B2 Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2016-06-21 US disclosed
US-9371286-B2 Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2016-06-21 US disclosed
EP-2617415-B1 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION (KR) 2016-04-20 EP disclosed
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells MSP CO., LTD. (KR) 2015-09-10 US disclosed
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells MSP CO., LTD. (KR) 2015-09-10 US disclosed
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells MSP CO., LTD. (KR) 2015-09-10 US disclosed
US-20140315947-A1 PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2014-10-23 US disclosed
US-20140315947-A1 PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2014-10-23 US disclosed
US-20130236969-A1 Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2013-09-12 US disclosed
EP-2617415-A2 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS Industry-Academic Cooperation Foundation, Yonsei University (KR) 2013-07-24 EP disclosed
WO-2012036512-A2 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS 연세대학교 산학협력단 (KR) 2012-03-22 WO disclosed
US-4053462-A UNSYMMETRICAL PHENYL AZO NAPHTHYL CHROMIUM COMPLEX DYES CIBA-GEIGY CORPORATION (US) 1977-10-11 US disclosed
US-4005065-A GOOD FASTNESS TO LIGHT, PERSPIRATION, FULLING, DECATIZING AND CARBONIZING CIBA-GEIGY CORPORATION (US) 1977-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130236969-A1 Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes COL2A1, MYADM, COL1A1 HKDC1 13/4885KMT2A 4177/4885MEN1 3963/4885
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells COL2A1, MYADM, COL1A1 HKDC1 13/4885KMT2A 3942/4885MEN1 3926/4885
US-20140315947-A1 PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS UQCRB, UQCRC1, UQCRC2 HKDC1 121/4885KMT2A 4308/4885MEN1 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.