SCHEMBL17850889

SCHEMBL17850889

O=C(c1ccc(N2c3ccccc3Oc3ccccc32)cc1)c1ccc(N2c3ccccc3Oc3ccccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 13/20 0.50
HDAC6 Q9UBN7 1/20 0.43
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
STAT1 P42224 1/20 0.42
RAB9A P51151 1/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
P2RX1 P51575 2/20 0.40
P2RX3 P56373 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SRD5A2 P31213 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17851140 1.00 P2RX4 (0.50) P2RX4HDAC6ALDH1A1MAPTSMN1; SMN2
SCHEMBL30874549 1.00 P2RX4 (0.50) P2RX4HDAC6ALDH1A1MAPTSMN1; SMN2
SCHEMBL17879153 0.97 P2RX4 (0.56) P2RX4ALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL17851082 0.95 P2RX4 (0.46) P2RX4HDAC6ALDH1A1MAPTSMN1; SMN2
SCHEMBL31059185 0.92 L3MBTL1 (0.50) P2RX4ALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL21843452 0.92 NPC1 (0.46) P2RX4ALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL21843450 0.92 ALDH1A1 (0.48) P2RX4ALDH1A1LMNASRD5A2
SCHEMBL17851088 0.92 L3MBTL1 (0.50) P2RX4ALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL17851130 0.92 P2RX4 (0.46) P2RX4HDAC6ALDH1A1HSD17B10NPSR1
SCHEMBL18884631 0.91 P2RX4 (0.43) P2RX4HDAC6LMNAP2RX1P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365857-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-16 US disclosed
US-20230365857-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-16 US disclosed
US-20230363257-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
US-20230363257-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
WO-2023124164-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE 昆山国显光电有限公司 2023-07-06 WO disclosed
US-11672174-B2 Pyrene-triazine derivative and applications thereof in organic electronic component GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2023-06-06 US disclosed
US-11672174-B2 Pyrene-triazine derivative and applications thereof in organic electronic component GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2023-06-06 US disclosed
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
US-11508927-B2 Organic electroluminescence device, preparation method thereof and display apparatus KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2022-11-22 US disclosed
US-20220149281-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY PANEL AND DISPLAY DEVICE KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2022-05-12 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
US-20170018600-A1 ORGANIC LIGHT-EMITTING DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-19 US disclosed
US-20170018600-A1 ORGANIC LIGHT-EMITTING DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-19 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
EP-3035401-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Kyushu University, National University Corporation (JP) 2016-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365857-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES H1-0, OR10J3, H1-2 P2RX4 699/4885HDAC6 3885/4885ALDH1A1 125/4885
US-11672174-B2 Pyrene-triazine derivative and applications thereof in organic electronic component TPR, TRPC5, TRPC4 P2RX4 381/4885HDAC6 4268/4885ALDH1A1 3751/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA P2RX4 2187/4885HDAC6 4183/4885ALDH1A1 269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.