SCHEMBL17864839

SCHEMBL17864839

CC(CNC(=O)OCCOC(=O)Nc1ccccc1)NC(=O)OCCOC(=O)Nc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.57
ALDH1A1 P00352 1/20 0.57
NPC1 O15118 4/20 0.55
RAB9A P51151 4/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
TSHR P16473 2/20 0.55
RECQL P46063 1/20 0.54
NPSR1 Q6W5P4 2/20 0.52
TP53 P04637 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.46
CHRNA7 P36544 1/20 0.45
MGLL Q99685 1/20 0.45
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18685289 0.95 LMNA (0.62) LMNAALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL19779246 0.82 LMNA (0.53) LMNAALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL17864863 0.79 NPC1 (0.68) LMNAALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL12459476 0.78 NPC1 (0.62) LMNAALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL17552070 0.77 ALDH1A1 (0.51) LMNAALDH1A1RAB9ASMN1; SMN2TSHR
SCHEMBL5540368 0.76 LMNA (0.62) LMNAALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL17550916 0.76 ACHE (0.39) SMN1; SMN2MEN1KMT2A
SCHEMBL5623097 0.76 NPC1 (0.68) LMNAALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL17346621 0.75 NPC1 (0.72) LMNAALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL10596423 0.75 NPC1 (0.72) LMNAALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-10338277-B2 Polarizing plate protective film, polarizing plate, and display FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-10031264-B2 Polarizing plate and display device FUJIFILM CORPORATION (JP) 2018-07-24 US disclosed
US-9817156-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-11-14 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9678249-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-20160291211-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291210-A1 POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291213-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160178809-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 LMNA 156/4885ALDH1A1 3809/4885NPC1 2545/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 LMNA 182/4885ALDH1A1 4014/4885NPC1 2604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.