Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860970 | 0.79 | MCL1 (0.45) | MCL1MAPK1GPR35STING1GAA | |
| SCHEMBL26778431 | 0.79 | MCL1 (0.65) | MCL1MAPK1STING1KDM4EMAPT | |
| SCHEMBL20937648 | 0.72 | MCL1 (0.58) | MCL1MAPK1GAATSHRKDM4E | |
| SCHEMBL1482745 | 0.70 | ALDH1A1 (0.48) | GAATSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL1509344 | 0.70 | MAPT (0.56) | MCL1MAPK1GRM1GAATSHR | |
| Hydrochloric Acid SCHEMBL8548770 | 0.70 | HTR1A (0.45) | MCL1MAPK1KDM4EMAPTALDH1A1 | |
| SCHEMBL14894804 | 0.70 | GPR35 (0.46) | MCL1MAPK1GPR35STING1MAPT | |
| SCHEMBL6614808 | 0.69 | MCL1 (0.45) | MCL1MAPK1GPR35STING1GAA | |
| SCHEMBL27697479 | 0.69 | STING1 (0.41) | MCL1MAPK1GPR35STING1BCL2 | |
| SCHEMBL9433145 | 0.68 | MCL1 (0.65) | MCL1MAPK1STING1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237547-B1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2019-03-20 | — | — | EP | disclosed |
| US-10196520-B2 | Direct dyes and composition comprising the dyes | KAO GERMANY GMBH (DE) | 2019-02-05 | — | — | US | disclosed |
| US-20170362436-A1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| EP-3237547-A1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | Kao Germany GmbH (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102207-A1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2016-06-30 | — | — | WO | disclosed |
| EP-3037485-A1 | Direct dyes and composition comprising the dyes | Kao Germany GmbH (DE) | 2016-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196520-B2 | Direct dyes and composition comprising the dyes | KRT18, TUBB4A, BRDT | MCL1 4226/4885MAPK1 2948/4885GPR35 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.