Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526223 | 0.89 | MEN1 (0.46) | AOC3TSHRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL18496621 | 0.88 | LMNA (0.40) | TSHRALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL21419430 | 0.86 | AOC3 (0.41) | AOC3TSHRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL18526413 | 0.84 | SMN1; SMN2 (0.39) | TSHRALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL18526414 | 0.84 | NPSR1 (0.43) | TSHRALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL18496686 | 0.83 | ALDH1A1 (0.36) | TSHRALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL20160880 | 0.79 | L3MBTL1 (0.48) | AOC3TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL18496687 | 0.78 | LMNA (0.44) | ALDH1A1SMN1; SMN2NPSR1L3MBTL1MEN1 | |
| SCHEMBL20160832 | 0.78 | TSHR (0.48) | AOC3TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL17874237 | 0.78 | AOC3 (0.41) | AOC3TSHRALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025493-A1 | QUINOLINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |