Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.62 |
| ▸ | MAOA | P21397 | 5/20 | 0.62 |
| ▸ | MAOB | P27338 | 5/20 | 0.62 |
| ▸ | ALDH2 | P05091 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892699 | 0.91 | ALDH2 (0.78) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL16357244 | 0.90 | ALDH1A1 (0.68) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL12386458 | 0.88 | KDM4E (0.54) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL10441792 | 0.88 | MAPT (0.74) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL12386532 | 0.88 | ALDH2 (0.57) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2349506 | 0.88 | KDM4E (0.83) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL17718164 | 0.85 | ALOX12 (0.55) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5814089 | 0.85 | XDH (0.78) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL12386455 | 0.85 | ALDH2 (0.57) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL2604722 | 0.84 | ALDH1A1 (0.72) | KDM4ENPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283313-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | NORTHWESTERN UNIVERSITY (US) | 2012-11-08 | — | — | US | disclosed |
| US-20070270332-A1 | METHODS AND ASSAYS USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE | VALLEE BERT L | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270332-A1 | METHODS AND ASSAYS USEFUL IN THE TREATMENT OF ALCOHOL DEPENDENCE OR ALCOHOL ABUSE | ADH1A, ADH5, ADH1C | KDM4E 4474/4885NPC1 2189/4885RAB9A 3813/4885 |
| US-20120283313-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | MAPK4, MAP4K4, MAP3K4 | KDM4E 242/4885NPC1 2582/4885RAB9A 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.