SCHEMBL17877640

SCHEMBL17877640

CCC1(CC)c2cc(C(=O)CC(C)C)ccc2-c2ccc(C(=NOC(C)=O)c3ccccc3)cc21

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.33
▸ KMT2A Q03164 4/20 0.33
▸ POLB P06746 3/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ MAPT P10636 3/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ RXRA P19793 1/20 0.32
▸ RXRB P28702 1/20 0.32
▸ RXRG P48443 1/20 0.32
▸ TDP1 Q9NUW8 2/20 0.32
▸ PPARG P37231 2/20 0.32
▸ PPARA Q07869 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ XBP1 P17861 1/20 0.31
▸ PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18012777 0.90 ALDH1A1 (0.39) ALDH1A1KMT2APOLBMEN1MAPT
SCHEMBL18351201 0.89 HPGD (0.39) ALDH1A1KMT2APOLBMEN1MAPT
SCHEMBL19186355 0.86 MAPT (0.41) ALDH1A1KMT2APOLBMEN1NPC1
SCHEMBL18012819 0.80 CYP2C19 (0.36) ALDH1A1KMT2APOLBMEN1MAPT
SCHEMBL18012772 0.78 RXRA (0.42) ALDH1A1KMT2APOLBMEN1MAPT
SCHEMBL18012625 0.77 MAPT (0.39) ALDH1A1KMT2APOLBMEN1NPC1
SCHEMBL17953240 0.76 PDK2 (0.45) ALDH1A1NPC1MAPTMAPK1TDP1
SCHEMBL17877625 0.75 HPGD (0.39) ALDH1A1KMT2AMEN1NPC1MAPT
SCHEMBL18012642 0.75 RAB9A (0.39) KMT2APOLBMEN1MAPTPDE4D
SCHEMBL17056225 0.73 KMT2A (0.38) ALDH1A1KMT2APOLBMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 — — US disclosed
US-9720319-B2 Colored composition, cured film, color filter, method for manufacturing color filter, solid-state imaging element, image display device, and compound FUJIFILM CORPORATION (JP) 2017-08-01 — — US disclosed
US-9720319-B2 Colored composition, cured film, color filter, method for manufacturing color filter, solid-state imaging element, image display device, and compound FUJIFILM CORPORATION (JP) 2017-08-01 — — US disclosed
US-9605154-B2 Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORPORATION (JP) 2017-03-28 — — US disclosed
US-9605154-B2 Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORPORATION (JP) 2017-03-28 — — US disclosed
US-20160216604-A1 COLORED COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2016-07-28 — — US disclosed
US-20160185969-A1 CURABLE COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGE PICKUP ELEMENT, PICTURE DISPLAY DEVICE, AND TRIARYLMETHANE COMPOUND FUJIFILM CORPORATION (JP) 2016-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 ALDH1A1 2079/4885KMT2A 1719/4885POLB 4072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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