SCHEMBL17877642

SCHEMBL17877642

N#Cc1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)-c1cc(-n3c4ccccc4c4ccccc43)ccc1CSC2

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
G6PD P11413 2/20 0.34
RORC P51449 5/20 0.33
USP14 P54578 3/20 0.33
PTGER4 P35408 2/20 0.33
ENPP3 O14638 1/20 0.33
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877655 1.00 KDM4E (0.34) KDM4EATML3MBTL1G6PDRORC
SCHEMBL17877695 1.00 KDM4E (0.34) KDM4EATML3MBTL1G6PDRORC
SCHEMBL17877657 1.00 KDM4E (0.34) KDM4EATML3MBTL1G6PDRORC
SCHEMBL17877792 0.96 ENPP3 (0.33) KDM4EATML3MBTL1G6PDRORC
SCHEMBL17877691 0.96 ENPP3 (0.33) KDM4EATML3MBTL1G6PDRORC
SCHEMBL17877656 0.94 USP14 (0.36) G6PDUSP14SLC6A4SLC6A3
SCHEMBL17877734 0.91 G6PD (0.31) KDM4EATML3MBTL1G6PDPTGER4
SCHEMBL17877808 0.89 PRF1 (0.33) G6PDPTGER4
SCHEMBL17875816 0.87 FLT3 (0.37) PTGER4
SCHEMBL17877670 0.86 KDM4E (0.35) KDM4EATML3MBTL1G6PDRORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 KDM4E 3120/4885ATM 1164/4885L3MBTL1 768/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 KDM4E 3120/4885ATM 1164/4885L3MBTL1 768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.