SCHEMBL17877808

SCHEMBL17877808

N#Cc1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)-c1ccc(-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)cc1CSC2

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRF1 P14222 2/20 0.33
PGR P06401 1/20 0.31
G6PD P11413 1/20 0.30
PTGER4 P35408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877734 0.96 G6PD (0.31) PRF1G6PDPTGER4
SCHEMBL17877732 0.92 MYC (0.38) PRF1PTGER4
SCHEMBL17877726 0.90 CYP11B2 (0.41)
SCHEMBL17877691 0.90 ENPP3 (0.33) PRF1G6PDPTGER4
SCHEMBL17877792 0.90 ENPP3 (0.33) PRF1G6PDPTGER4
SCHEMBL17875761 0.89 KDM4E (0.37)
SCHEMBL17877695 0.89 KDM4E (0.34) G6PDPTGER4
SCHEMBL17877657 0.89 KDM4E (0.34) G6PDPTGER4
SCHEMBL17877642 0.89 KDM4E (0.34) G6PDPTGER4
SCHEMBL17877655 0.89 KDM4E (0.34) G6PDPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 PRF1 1835/4885PGR 1766/4885G6PD 2202/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 PRF1 1835/4885PGR 1766/4885G6PD 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.