SCHEMBL17879112

SCHEMBL17879112

c1ccc(N(c2ccccc2)c2ccc(-c3nc4nc(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)c(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)nc4nc3-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.47
L3MBTL1 Q9Y468 4/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
TP53 P04637 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ADK P55263 3/20 0.43
GAA P10253 1/20 0.39
CRHBP P24387 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17879120 0.98 TDP1 (0.45) TDP1L3MBTL1MEN1KMT2ALMNA
SCHEMBL18216992 0.98 TDP1 (0.45) TDP1L3MBTL1MEN1KMT2ALMNA
SCHEMBL17879117 0.98 TDP1 (0.45) TDP1L3MBTL1MEN1KMT2ALMNA
SCHEMBL17879114 0.96 TDP1 (0.48) TDP1L3MBTL1MEN1KMT2ALMNA
SCHEMBL17879138 0.94 ADK (0.43) TDP1L3MBTL1MEN1KMT2ALMNA
SCHEMBL17879127 0.91 TDP1 (0.50) TDP1L3MBTL1MEN1KMT2ALMNA
SCHEMBL14447304 0.89 ALDH1A1 (0.48) TDP1L3MBTL1MEN1KMT2ALMNA
SCHEMBL14447268 0.89 ALDH1A1 (0.48) TDP1L3MBTL1MEN1KMT2ALMNA
SCHEMBL14447317 0.89 ALDH1A1 (0.48) TDP1L3MBTL1MEN1KMT2ALMNA
SCHEMBL5467467 0.89 ALDH1A1 (0.48) TDP1L3MBTL1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND TERB1, TERT, TCOF1 TDP1 2666/4885L3MBTL1 297/4885MEN1 3524/4885
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 TDP1 2666/4885L3MBTL1 297/4885MEN1 3524/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA TDP1 1930/4885L3MBTL1 251/4885MEN1 1375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.