SCHEMBL1788677

SCHEMBL1788677

C=C(CCC=Cc1ccc(OC)c(OC)c1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
ALDH1A1 P00352 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
MAPK1 P28482 1/20 0.55
HSD17B10 Q99714 1/20 0.55
NFE2L2 Q16236 1/20 0.54
GRIK1 P39086 1/20 0.50
GRIK2 Q13002 1/20 0.50
KMT2A Q03164 3/20 0.49
ABCG2 Q9UNQ0 2/20 0.49
MEN1 O00255 2/20 0.49
SNCA P37840 1/20 0.48
POLB P06746 1/20 0.48
CYP1A1 P04798 3/20 0.48
CYP1B1 Q16678 2/20 0.48
CYP1A2 P05177 1/20 0.48
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1788715 0.90 KDM4E (0.57) KDM4EALDH1A1HPGDALOX15MAPK1
SCHEMBL1788190 0.89 KDM4E (0.63) KDM4EALDH1A1KMT2AMEN1SNCA
SCHEMBL1792503 0.87 APP (0.60) KDM4ESMN1; SMN2ALDH1A1HPGDKMT2A
SCHEMBL1789695 0.85 ALDH1A1 (0.54) KDM4EALDH1A1HPGDHSD17B10CYP1A1
SCHEMBL1791116 0.85 PTGS1 (0.54) KDM4EALDH1A1NFE2L2CYP1A2PTGS1
SCHEMBL1788486 0.83 PTGS1 (0.48) KDM4ESMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL1790768 0.82 THRB (0.51) GRIK1GRIK2NPC1RAB9A
SCHEMBL29972668 0.80 JUN (0.49) KDM4ESMN1; SMN2ALDH1A1HPGDALOX15
SCHEMBL28912356 0.80 JUN (0.49) KDM4ESMN1; SMN2ALDH1A1HPGDALOX15
Acetic Acid SCHEMBL8820510 0.79 SMN1; SMN2 (0.59) KDM4ESMN1; SMN2ALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-7041416-B2 Photosensitive resin composition, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS KDM4E 114/4885SMN1; SMN2 4176/4885ALDH1A1 1226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.