SCHEMBL1790768

SCHEMBL1790768

C=C(CCC=Cc1ccc(OC)cc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.51
ATM Q13315 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
GSK3B P49841 2/20 0.50
F3 P13726 2/20 0.49
LTB4R Q15722 1/20 0.47
LTB4R2 Q9NPC1 1/20 0.47
GRIK1 P39086 1/20 0.47
GRIK2 Q13002 1/20 0.47
BACE1 P56817 1/20 0.47
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46
PTGER2 P43116 1/20 0.46
BCHE P06276 1/20 0.46
CYP3A4 P08684 1/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
HDAC3 O15379 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5965887 0.86 NPC1 (0.53) NPC1RAB9ARELA
SCHEMBL16710517 0.84 NPC1 (0.65) THRBATMNPC1RAB9AGSK3B
SCHEMBL1789485 0.83 RAB9A (0.47) NPC1RAB9AGRIK1GRIK2CYP3A4
SCHEMBL1788677 0.82 KDM4E (0.55) NPC1RAB9AGRIK1GRIK2
SCHEMBL699686 0.81 PAM (0.52) F3GRIK1GRIK2PTGER4PTGER3
SCHEMBL8115998 0.81 PAM (0.52) F3GRIK1GRIK2PTGER4PTGER3
SCHEMBL5965927 0.80 GRIK1 (0.44) GRIK1GRIK2BCHEHDAC3HDAC1
SCHEMBL7650816 0.80 GSK3B (0.54) THRBATMNPC1RAB9AGSK3B
SCHEMBL7650810 0.80 GSK3B (0.54) THRBATMNPC1RAB9AGSK3B
SCHEMBL1788715 0.80 KDM4E (0.57) THRBGSK3BF3BACE1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-7041416-B2 Photosensitive resin composition, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS THRB 1303/4885ATM 1091/4885NPC1 4759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.