Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31373437 | 0.80 | KDM4E (0.47) | SIGMAR1KDM1AANPEPKDM4EALDH1A1 | |
| SCHEMBL6941 | 0.78 | PLAU (0.68) | PLAUSIGMAR1CA12CA1CA2 | |
| SCHEMBL29365759 | 0.78 | PLAU (0.68) | PLAUSIGMAR1CA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL28756078 | 0.78 | DPP4 (0.38) | CA12CA1CA2CA7CA14 | |
| Trifluoroacetic Acid SCHEMBL4280586 | 0.76 | KDM4E (0.42) | SIGMAR1KDM1AANPEPKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL29384401 | 0.76 | PLAU (0.65) | PLAUSIGMAR1CA1CA2KDM1A | |
| Hydrochloric Acid SCHEMBL151479 | 0.76 | PLAU (0.65) | PLAUSIGMAR1CA1CA2KDM1A | |
| Trifluoroacetic Acid SCHEMBL4652712 | 0.75 | ALDH1A1 (0.41) | SIGMAR1KDM1AKDM4EALDH1A1LMNA | |
| SCHEMBL16595708 | 0.74 | PNMT (0.39) | CES1ALDH1A1MAPTPNMT | |
| Hydrochloric Acid SCHEMBL4543313 | 0.74 | PLAU (0.62) | PLAUSIGMAR1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124559-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | SMITHKLINE BEECHAM CORPORATION (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124559-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | OPRL1, OPRM1, OPRK1 | PLAU 3414/4885CES1 3131/4885SIGMAR1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.