Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.75 |
| ▸ | CYCS | P99999 | 4/20 | 0.73 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140681 | 0.95 | TOP1 (0.67) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL11339474 | 0.95 | TOP1 (0.75) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL28919688 | 0.94 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL11334086 | 0.94 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL22332272 | 0.92 | TOP1 (0.70) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL29354037 | 0.87 | TOP1 (1.00) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL709532 | 0.87 | TOP1 (1.00) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL3047596 | 0.85 | TOP1 (0.97) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL19640853 | 0.85 | CYCS (1.00) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL1497141 | 0.85 | TOP1 (0.97) | TOP1CYCSENPP2ABCG2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10111842-B2 | Eutectic solvents and uses thereof | UNIVERSITY OF OSLO (NO) | 2018-10-30 | — | — | US | claimed |
| US-20180000753-A1 | EUTECTIC SOLVENTS AND USES THEREOF | UNIVERSITY OF OSLO (NO) | 2018-01-04 | — | — | US | claimed |
| WO-2016108083-A1 | EUTECTIC SOLVENTS AND USES THEREOF | UNIVERSITY OF OSLO (NO) | 2016-07-07 | — | — | WO | claimed |
| US-20230302144-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | ONCOSELECT THERAPEUTICS, LLC (US) | 2023-09-28 | — | — | US | disclosed |
| US-11590233-B2 | Porphyrin compounds and compositions useful for treating cancer | ONCOSELECT THERAPEUTICS, LLC (US) | 2023-02-28 | — | — | US | disclosed |
| US-20190184021-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | ONCOSELECT THERAPEUTICS, LLC | 2019-06-20 | — | — | US | disclosed |
| EP-3471774-A1 | PORPHYRIN COMPOUNDS AND COMPOSITIONS USEFUL FOR TREATING CANCER | Oncoselect Therapeutics, LLC (US) | 2019-04-24 | — | — | EP | disclosed |
| US-10111842-B2 | Eutectic solvents and uses thereof | UNIVERSITY OF OSLO (NO) | 2018-10-30 | — | — | US | disclosed |
| US-20180000753-A1 | EUTECTIC SOLVENTS AND USES THEREOF | UNIVERSITY OF OSLO (NO) | 2018-01-04 | — | — | US | disclosed |
| WO-2017218959-A1 | PORPHYRIN COMPOUNDS AND COMPOSITIONS USEFUL FOR TREATING CANCER | ONCOSELECT THERAPEUTICS, LLC (US) | 2017-12-21 | — | — | WO | disclosed |
| WO-2016108083-A1 | EUTECTIC SOLVENTS AND USES THEREOF | UNIVERSITY OF OSLO (NO) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10111842-B2 | Eutectic solvents and uses thereof | UROD, DUS2, ALAD | TOP1 939/4885CYCS 2243/4885STAT3 2370/4885 |
| US-20230302144-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | KIT, HCCS, PPIF | TOP1 176/4885CYCS 256/4885STAT3 1427/4885 |
| US-11590233-B2 | Porphyrin compounds and compositions useful for treating cancer | KIT, HCCS, PPIF | TOP1 176/4885CYCS 256/4885STAT3 1427/4885 |
| US-20190184021-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | TK2, KIT, HCCS | TOP1 228/4885CYCS 315/4885STAT3 923/4885 |
| US-20180000753-A1 | EUTECTIC SOLVENTS AND USES THEREOF | UROD, DUS2, ALAD | TOP1 939/4885CYCS 2243/4885STAT3 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.