Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400285 | 1.00 | TACR1 (0.43) | TACR1MMP9MMP8RCE1HTT | |
| SCHEMBL24450258 | 0.83 | MMP9 (0.49) | TACR1MMP9MMP8RCE1HTT | |
| SCHEMBL22040557 | 0.82 | ALDH1A1 (0.43) | TACR1MMP9MMP8RCE1HTT | |
| SCHEMBL17894178 | 0.82 | ALDH1A1 (0.43) | TACR1MMP9MMP8RCE1HTT | |
| SCHEMBL19481444 | 0.75 | RCE1 (0.47) | TACR1MMP9MMP8RCE1HTT | |
| SCHEMBL19435356 | 0.73 | SLC1A3 (0.37) | TACR1RCE1HTTTSHRMAPT | |
| SCHEMBL17894189 | 0.73 | SLC1A3 (0.37) | TACR1RCE1HTTTSHRMAPT | |
| SCHEMBL5018878 | 0.73 | RCE1 (0.49) | TACR1MMP9MMP8RCE1HTT | |
| SCHEMBL20463639 | 0.73 | RCE1 (0.49) | TACR1MMP9MMP8RCE1HTT | |
| SCHEMBL18661849 | 0.71 | RCE1 (0.51) | TACR1MMP9MMP8RCE1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240423207-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2024-12-26 | — | — | US | disclosed |
| US-12114660-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2024-10-15 | — | — | US | disclosed |
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2023-11-23 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-20220159962-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2022-05-26 | — | — | US | disclosed |
| US-20220159962-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC (US) | 2022-05-26 | — | — | US | disclosed |
| US-11284620-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2022-03-29 | — | — | US | disclosed |
| EP-3808181-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2021-04-21 | — | — | EP | disclosed |
| US-10182568-B2 | Use of picolinamide compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-22 | — | — | US | disclosed |
| US-10182568-B2 | Use of picolinamide compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-22 | — | — | US | disclosed |
| EP-3240424-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-3240773-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow AgroSciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-10-12 | — | — | US | disclosed |
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-10-12 | — | — | US | disclosed |
| WO-2016122802-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016109257-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | TACR1 3412/4885MMP9 1940/4885MMP8 2040/4885 |
| US-10182568-B2 | Use of picolinamide compounds as fungicides | PFAS, FKBP2, FKBP14 | TACR1 1788/4885MMP9 4037/4885MMP8 3330/4885 |
| US-20220159962-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | TACR1 3412/4885MMP9 1940/4885MMP8 2040/4885 |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | PFAS, FKBP2, FKBP14 | TACR1 1788/4885MMP9 4037/4885MMP8 3330/4885 |
| US-20230371516-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | TACR1 3412/4885MMP9 1940/4885MMP8 2040/4885 |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | TACR1 3412/4885MMP9 1940/4885MMP8 2040/4885 |
| US-12114660-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | TACR1 3412/4885MMP9 1940/4885MMP8 2040/4885 |
| US-11284620-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | TACR1 3412/4885MMP9 1940/4885MMP8 2040/4885 |
| US-20240423207-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | TACR1 3412/4885MMP9 1940/4885MMP8 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.