Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22474188 | 1.00 | SIGMAR1 (0.38) | SIGMAR1SLC6A2SLC6A4SLC6A3NAAA | |
| SCHEMBL19757660 | 0.83 | GPR88 (0.38) | SIGMAR1 | |
| SCHEMBL17900613 | 0.82 | CYP3A4 (0.35) | — | |
| SCHEMBL17895071 | 0.78 | CYP1A2 (0.40) | — | |
| SCHEMBL17900550 | 0.77 | GPR88 (0.38) | — | |
| SCHEMBL14461655 | 0.76 | HTT (0.40) | SIGMAR1SLC6A2SLC6A4SLC6A3HTT | |
| SCHEMBL28907529 | 0.73 | HTT (0.47) | SLC6A2SLC6A4SLC6A3HTT | |
| SCHEMBL17896182 | 0.73 | HTT (0.47) | SLC6A2SLC6A4SLC6A3HTT | |
| SCHEMBL22394295 | 0.71 | ADRA2A (0.39) | — | |
| SCHEMBL22474334 | 0.69 | GPR88 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205399-B | Picolinamides as fungicides | 美国陶氏益农公司 | 2021-01-29 | — | — | CN | disclosed |
| EP-3255991-B1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-3240413-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-13 | — | — | EP | disclosed |
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-10-08 | — | — | US | disclosed |
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-10-08 | — | — | US | disclosed |
| US-10173981-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-10173981-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180000085-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| US-20180000075-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| EP-3240412-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-3240413-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | Dow Agrosciences LLC (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109288-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109289-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180000075-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | SIGMAR1 1339/4885SLC6A2 3163/4885SLC6A4 2413/4885 |
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | SIGMAR1 1339/4885SLC6A2 3163/4885SLC6A4 2413/4885 |
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | SIGMAR1 841/4885SLC6A2 2336/4885SLC6A4 1821/4885 |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | PFAS, CYP1A2, CYP4F12 | SIGMAR1 824/4885SLC6A2 2451/4885SLC6A4 1772/4885 |
| US-10173981-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | SIGMAR1 841/4885SLC6A2 2336/4885SLC6A4 1821/4885 |
| US-20180000085-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CYP1A2, CYP51A1 | SIGMAR1 1430/4885SLC6A2 3574/4885SLC6A4 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.