SCHEMBL17899379

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17888600	0.88	AKR1C3 (0.39)	RAB9ANPC1MEN1KMT2AL3MBTL1
	SCHEMBL17899158	0.84	AKR1C3 (0.41)	RAB9ANPC1MEN1KMT2AL3MBTL1
	SCHEMBL17899152	0.83	AKR1C3 (0.38)	RAB9ANPC1MEN1KMT2AAKR1C3
	SCHEMBL17888618	0.81	AKR1C3 (0.45)	RAB9AMEN1KMT2AAKR1C3AKR1C2
	SCHEMBL17931447	0.80	MAPT (0.40)	RAB9AL3MBTL1AKR1C3AKR1C2ALDH1A1
	SCHEMBL17888611	0.78	ALDH1A1 (0.43)	ALDH1A1MAPTKDM4E
	SCHEMBL23190672	0.78	SPIN1 (0.38)	AKR1C3AKR1C2MAPTSPIN1
	SCHEMBL17888653	0.76	AKR1C3 (0.39)	AKR1C3AKR1C2ALDH1A1MAPTKDM4E
	SCHEMBL17888547	0.75	MEN1 (0.38)	RAB9AMEN1KMT2AAKR1C3AKR1C2
	SCHEMBL17888616	0.75	CETP (0.41)	AKR1C3AKR1C2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.