SCHEMBL17899158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17888600	0.93	AKR1C3 (0.39)	AKR1C3AKR1C2SIRT2KDM4EALDH1A1
	SCHEMBL17931447	0.88	MAPT (0.40)	AKR1C3AKR1C2SIRT2KDM4EALDH1A1
	SCHEMBL17888635	0.88	AKR1C3 (0.41)	AKR1C3AKR1C2SIRT2KDM4EALDH1A1
	SCHEMBL17899152	0.87	AKR1C3 (0.38)	AKR1C3AKR1C2SPIN1TBK1F10
	SCHEMBL23190672	0.85	SPIN1 (0.38)	AKR1C3AKR1C2SIRT2SPIN1TBK1
	SCHEMBL17899379	0.84	RAB9A (0.38)	AKR1C3AKR1C2KDM4EALDH1A1SPIN1
	SCHEMBL17888611	0.84	ALDH1A1 (0.43)	KDM4EALDH1A1TBK1
	SCHEMBL17899405	0.83	KDM4E (0.40)	KDM4EALDH1A1TBK1L3MBTL1GAA
	SCHEMBL17888618	0.83	AKR1C3 (0.45)	AKR1C3AKR1C2KDM4EALDH1A1SPIN1
	SCHEMBL17888646	0.82	TBK1 (0.38)	SIRT2TBK1F10PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.