Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 3/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17902148 | 1.00 | MAPT (0.33) | MAPTKMT2AHTTMEN1CARM1 | |
| SCHEMBL17902592 | 0.94 | MEN1 (0.36) | MAPTKMT2AHTTMEN1SLC9A1 | |
| SCHEMBL20661966 | 0.91 | GRM1 (0.34) | MAPTKMT2AHTTMEN1CARM1 | |
| SCHEMBL17902142 | 0.89 | MEN1 (0.36) | MAPTKMT2AHTTMEN1CARM1 | |
| SCHEMBL17902230 | 0.87 | PDE10A (0.36) | MAPTKMT2AHTTMEN1 | |
| SCHEMBL17902229 | 0.87 | PDE10A (0.36) | MAPTKMT2AHTTMEN1 | |
| SCHEMBL17902311 | 0.86 | CES2 (0.37) | MAPTKMT2AMEN1CARM1PRMT6 | |
| SCHEMBL17902368 | 0.86 | CTSA (0.37) | HTTCTSA | |
| SCHEMBL17902367 | 0.86 | CTSA (0.37) | HTTCTSA | |
| SCHEMBL17902378 | 0.85 | MEN1 (0.35) | MAPTKMT2AHTTMEN1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2020-03-17 | — | — | US | disclosed |
| US-10182568-B2 | Use of picolinamide compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-22 | — | — | US | disclosed |
| WO-2016122802-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016109257-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10182568-B2 | Use of picolinamide compounds as fungicides | PFAS, FKBP2, FKBP14 | MAPT 1956/4885KMT2A 3515/4885HTT 3837/4885 |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | MAPT 1306/4885KMT2A 3102/4885HTT 3579/4885 |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | MAPT 1306/4885KMT2A 3102/4885HTT 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.