Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17902311 | 0.95 | CES2 (0.37) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL17902234 | 0.92 | POLB (0.34) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL17902231 | 0.92 | POLB (0.34) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL17902148 | 0.91 | MAPT (0.33) | MEN1KMT2ACARM1PRMT6MAPT | |
| SCHEMBL17902133 | 0.91 | MAPT (0.33) | MEN1KMT2ACARM1PRMT6MAPT | |
| SCHEMBL17902377 | 0.91 | GPR139 (0.36) | CARM1PRMT6POLBGPR139MAPT | |
| SCHEMBL17902588 | 0.90 | KLK7 (0.37) | MEN1KMT2AGPR139MAPTLMNA | |
| SCHEMBL26321695 | 0.90 | KLK7 (0.37) | MEN1KMT2AGPR139MAPTLMNA | |
| SCHEMBL17902359 | 0.90 | POLB (0.33) | MEN1KMT2ATDP1CARM1PRMT6 | |
| SCHEMBL17902357 | 0.90 | KLK7 (0.37) | MEN1KMT2AGPR139MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2020-03-17 | — | — | US | disclosed |
| US-10182568-B2 | Use of picolinamide compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10182568-B2 | Use of picolinamide compounds as fungicides | PFAS, FKBP2, FKBP14 | GRM1 452/4885MEN1 2036/4885CYP1A2 5/4885 |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | GRM1 1190/4885MEN1 2200/4885CYP1A2 3/4885 |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | GRM1 1190/4885MEN1 2200/4885CYP1A2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.