Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17902244 | 0.89 | LPAR1 (0.40) | LPAR1ACHETAS1R3TAS1R1 | |
| SCHEMBL20348365 | 0.86 | LPAR1 (0.38) | LPAR1ACHENPC1RAB9A | |
| SCHEMBL17902137 | 0.86 | ALDH1A1 (0.42) | NPC1 | |
| SCHEMBL17902243 | 0.86 | ADRA2A (0.44) | LPAR1NPC1 | |
| SCHEMBL17902355 | 0.85 | GRIN2D (0.41) | LPAR1 | |
| SCHEMBL17902592 | 0.85 | MEN1 (0.36) | — | |
| SCHEMBL26321679 | 0.85 | GRIN2D (0.41) | LPAR1 | |
| SCHEMBL20662037 | 0.84 | GRM1 (0.36) | TAS1R3TAS1R1 | |
| SCHEMBL17902368 | 0.83 | CTSA (0.37) | TAS1R3TAS1R1 | |
| SCHEMBL17902367 | 0.83 | CTSA (0.37) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | CORTEVA AGRISCIENCE LLC (US) | 2023-09-12 | — | — | US | disclosed |
| EP-3808181-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-3240773-B9 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-3240424-B1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-16 | — | — | EP | disclosed |
| EP-3240773-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-06-03 | — | — | EP | disclosed |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2020-03-17 | — | — | US | disclosed |
| US-10182568-B2 | Use of picolinamide compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-22 | — | — | US | disclosed |
| WO-2016122802-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016109257-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10182568-B2 | Use of picolinamide compounds as fungicides | PFAS, FKBP2, FKBP14 | LPAR1 2667/4885ACHE 1776/4885NPC1 1509/4885 |
| US-11751568-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | LPAR1 3045/4885ACHE 2340/4885NPC1 1093/4885 |
| US-10588318-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | LPAR1 3045/4885ACHE 2340/4885NPC1 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.