SCHEMBL1789485

SCHEMBL1789485

C=C(CCC=Cc1ccc(C)cc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.47
KMT2A Q03164 1/20 0.47
GRIK1 P39086 1/20 0.43
GRIK2 Q13002 1/20 0.43
FOS P01100 1/20 0.42
JUN P05412 1/20 0.42
MAPT P10636 3/20 0.41
CYP3A4 P08684 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
LMNA P02545 2/20 0.40
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
CYP1B1 Q16678 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699686 0.85 PAM (0.52) GRIK1GRIK2MAPTALDH1A1LMNA
SCHEMBL8115998 0.85 PAM (0.52) GRIK1GRIK2MAPTALDH1A1LMNA
SCHEMBL5965927 0.84 GRIK1 (0.44) GRIK1GRIK2MAPTALDH1A1CYP1B1
SCHEMBL1790768 0.83 THRB (0.51) RAB9AGRIK1GRIK2CYP3A4NPC1
SCHEMBL13870216 0.83 KMT2A (0.62) RAB9AKMT2AGRIK1GRIK2FOS
SCHEMBL5965887 0.81 NPC1 (0.53) RAB9AKMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL9674067 0.80 RAB9A (0.49) RAB9AKMT2AGRIK1GRIK2FOS
SCHEMBL1791768 0.79 GRIK1 (0.48) RAB9AKMT2AGRIK1GRIK2MAPT
SCHEMBL1788908 0.79 PDE5A (0.45) RAB9AKMT2AMAPTLMNACYP1B1
SCHEMBL5965920 0.78 ALDH1A1 (0.56) KMT2AMAPTCYP3A4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-7041416-B2 Photosensitive resin composition, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS RAB9A 4200/4885KMT2A 476/4885GRIK1 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.