Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17913056 | 0.88 | LMNA (0.62) | MAPTGAARAB9ATDP1L3MBTL1 | |
| SCHEMBL17913101 | 0.87 | GAA (0.56) | MAPTGAARAB9ANPC1POLB | |
| SCHEMBL17913049 | 0.87 | GAA (0.56) | MAPTGAARAB9ANPC1POLB | |
| SCHEMBL17913052 | 0.85 | PGR (0.61) | MAPTGAATDP1CA9CA12 | |
| SCHEMBL17913083 | 0.85 | PGR (0.61) | MAPTGAATDP1CA9CA12 | |
| SCHEMBL17913038 | 0.84 | FAAH (0.55) | MAPTGAARAB9ANPC1TDP1 | |
| SCHEMBL6285944 | 0.84 | RAB9A (0.66) | MAPTGAARAB9ANPC1POLB | |
| SCHEMBL6285948 | 0.84 | RAB9A (0.66) | MAPTGAARAB9ANPC1POLB | |
| SCHEMBL17913102 | 0.81 | CA12 (0.56) | MAPTGAATDP1CA9CA12 | |
| SCHEMBL17913042 | 0.80 | ALDH1A1 (0.60) | MAPTGAATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016111658-A1 | SYNTHESIS OF THIOSEMICARBAZONE DERIVATIVES COMPRISING SULPHONAMIDE GROUP WITH POTENTIAL ANTICONVULSANT ACTIVITY | IYIDOGAN AYSEGUL (TR) | 2016-07-14 | — | — | WO | disclosed |