SCHEMBL17917849

SCHEMBL17917849

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4cccc5c4oc4ccccc45)c(-c4ccccc4)c3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 3/20 0.49
▸ GGPS1 O95749 1/20 0.39
▸ PRKDC P78527 7/20 0.38
▸ PTGES2 Q9H7Z7 1/20 0.36
▸ CDC14B O60729 2/20 0.35
▸ CDC14A Q9UNH5 2/20 0.35
▸ PIK3CD O00329 1/20 0.35
▸ PIK3CB P42338 1/20 0.35
▸ PLA2G2A P14555 3/20 0.35
▸ PLA2G4A P47712 3/20 0.35
▸ ATM Q13315 1/20 0.34
▸ TNKS O95271 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ PLA2G10 O15496 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ CSF1R P07333 1/20 0.33
▸ PDGFRB P09619 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ KIT P10721 1/20 0.33
▸ FLT3 P36888 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17917957 1.00 ALOX5 (0.49) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL17917828 1.00 ALOX5 (0.49) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL17918109 1.00 ALOX5 (0.49) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL17918104 0.99 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL22159503 0.99 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL23438631 0.99 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL19597901 0.99 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL23438843 0.99 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL25628896 0.96 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL23438504 0.96 ALOX5 (0.50) ALOX5GGPS1PRKDCPTGES2CDC14B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4170001-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2023-04-26 — — EP disclosed
EP-3244465-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-04-20 — — EP disclosed
US-11158813-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 — — US disclosed
US-20210163411-A1 COMPOUND HAVING TRIARYLAMINE STRUCTURE AS CORE, AND PREPARATION METHOD THEREFOR JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) 2021-06-03 — — US disclosed
US-20210143326-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2021-05-13 — — US disclosed
US-20200365813-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2020-11-19 — — US disclosed
US-10566540-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-18 — — US disclosed
US-10505119-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2019-12-10 — — US disclosed
US-20180026198-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-04 — — US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 — — US disclosed
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE SFC CO., LTD. (KR) 2017-11-30 — — US disclosed
EP-3244465-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 — — EP disclosed
WO-2016125706-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-08-11 — — WO disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11158813-B2 Organic electroluminescent device KCNN2, SLC7A5, KCNH3 ALOX5 520/4885GGPS1 3542/4885PRKDC 4342/4885
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, KCNH1 ALOX5 1877/4885GGPS1 2830/4885PRKDC 4677/4885
US-10505119-B2 Organic electroluminescence device AHR, ARNT, NAT1 ALOX5 1998/4885GGPS1 3830/4885PRKDC 4790/4885
US-20170346009-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, ARNT ALOX5 1636/4885GGPS1 3133/4885PRKDC 4716/4885
US-20210163411-A1 COMPOUND HAVING TRIARYLAMINE STRUCTURE AS CORE, AND PREPARATION METHOD THEREFOR WEE1, WEE2, ALOX12 ALOX5 41/4885GGPS1 72/4885PRKDC 4163/4885
US-10566540-B2 Organic electroluminescent device KCNN2, SLC7A5, KCNN1 ALOX5 1257/4885GGPS1 3198/4885PRKDC 4607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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