SCHEMBL17917876

SCHEMBL17917876

c1ccc(-c2nc(-c3ccc(-c4ccc5ccccc5c4)cc3)cc(-c3cccc(-c4cccnc4)c3)n2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 8/20 0.68
CYP11B1 P15538 7/20 0.68
CYP19A1 P11511 6/20 0.68
CYP17A1 P05093 4/20 0.68
CYP1A1 P04798 1/20 0.52
CYP1B1 Q16678 1/20 0.52
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
SIRT2 Q8IXJ6 1/20 0.51
CYP2A6 P11509 1/20 0.48
KMO O15229 1/20 0.48
DHODH Q02127 1/20 0.47
PGR P06401 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17808069 1.00 CYP11B2 (0.68) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1
SCHEMBL19397483 1.00 CYP11B2 (0.68) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1
SCHEMBL17807977 1.00 CYP11B2 (0.68) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1
SCHEMBL22809368 1.00 CYP11B2 (0.68) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1
SCHEMBL17917898 1.00 CYP11B2 (0.68) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1
SCHEMBL17808063 0.99 CYP11B2 (0.69) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1
SCHEMBL21725381 0.99 CYP11B2 (0.69) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1
SCHEMBL17918124 0.99 CYP11B2 (0.69) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1
SCHEMBL17918135 0.97 CYP11B2 (0.68) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1
SCHEMBL21725413 0.97 CYP11B2 (0.68) CYP11B2CYP11B1CYP19A1CYP17A1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3309235-B1 ORGANIC LIGHT EMITTING ELEMENT HAVING HIGH EFFICIENCY SFC CO LTD (KR) 2023-10-18 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-10950802-B2 Organic light-emitting diode with high efficiency SFC CO., LTD. (KR) 2021-03-16 US disclosed
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2020-09-24 US disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-10559759-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-11 US disclosed
US-20190273216-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-09-05 US disclosed
US-10276800-B2 Organic electroluminescence device having at least an a node, a hole injection layer, a first hole transport layer. A second hole transport layer a luminous layer, an electron transport layer, and a cathode HODOGAYA CHEMICAL CO., LTD. (JP) 2019-04-30 US disclosed
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-01-03 US disclosed
US-20180166638-A1 Organic light-emitting diode with high efficiency SFC CO., LTD. (KR) 2018-06-14 US disclosed
US-20170346015-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-30 US disclosed
EP-3244464-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-02 US disclosed
EP-3240057-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-01 EP disclosed
EP-3229284-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-10-11 EP disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
EP-3156402-A1 PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-04-19 EP disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10276800-B2 Organic electroluminescence device having at least an a node, a hole injection layer, a first hole transport layer. A second hole transport layer a luminous layer, an electron transport layer, and a cathode SLC29A1, SLC29A2, NUDT1 CYP11B2 1707/4885CYP11B1 1848/4885CYP19A1 1602/4885
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 CYP11B2 470/4885CYP11B1 272/4885CYP19A1 42/4885
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B2 2329/4885CYP11B1 1800/4885CYP19A1 1535/4885
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B2 2329/4885CYP11B1 1800/4885CYP19A1 1535/4885
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLC43A1, SLC7A5, SLCO4C1 CYP11B2 1506/4885CYP11B1 1290/4885CYP19A1 283/4885
US-10559759-B2 Organic electroluminescent device SLC29A2, SLC29A1, SLCO4C1 CYP11B2 880/4885CYP11B1 1190/4885CYP19A1 1008/4885
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE NUDT1, SLCO4C1, SLC7A5 CYP11B2 1456/4885CYP11B1 1637/4885CYP19A1 1533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.