Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17933018 | 0.97 | HTT (0.49) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL14430339 | 0.93 | HTT (0.59) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL14430332 | 0.90 | HTT (0.55) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL17935888 | 0.78 | ADRB2 (0.52) | MEN1KMT2ANPSR1KDM4EADRB2 | |
| SCHEMBL14430331 | 0.77 | HTT (0.66) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL340937 | 0.76 | HTT (0.69) | HTTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL14441288 | 0.76 | ALDH1A1 (0.50) | MEN1KMT2ANPSR1KDM4EADRB2 | |
| SCHEMBL14441289 | 0.75 | MEN1 (0.51) | MEN1KMT2ANPSR1KDM4EADRB2 | |
| SCHEMBL14430409 | 0.75 | PTGS2 (0.48) | MEN1KMT2AKDM4EADRB2ADRB1 | |
| SCHEMBL4415350 | 0.75 | HTT (0.75) | HTTMEN1KMT2ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170368185-A9 | METHOD OF PREPARING DENDRITIC DRUGS | CHAI MINGHUI (CN) | 2017-12-28 | — | — | US | disclosed |
| US-20160206746-A1 | METHOD OF PREPARING DENDRITIC DRUGS | CHAI MINGHUI (CN) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160206746-A1 | METHOD OF PREPARING DENDRITIC DRUGS | MYD88, TLR3, TLR6 | HTT 3647/4885MEN1 3220/4885KMT2A 4308/4885 |
| US-20170368185-A9 | METHOD OF PREPARING DENDRITIC DRUGS | MYD88, TLR3, TLR6 | HTT 3647/4885MEN1 3220/4885KMT2A 4308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.