Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 9/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17943840 | 0.88 | TP53 (0.51) | CYP3A4KDM4EMEN1KMT2AMAPT | |
| SCHEMBL17940149 | 0.82 | ALDH1A1 (0.39) | CYP3A4KDM4EMEN1KMT2AMAPT | |
| SCHEMBL17940142 | 0.81 | CYP3A4 (0.68) | CYP3A4KDM4EMEN1KMT2AMAPT | |
| SCHEMBL26661232 | 0.80 | KDM4E (0.65) | CYP3A4KDM4EMEN1KMT2AMAPT | |
| SCHEMBL17940164 | 0.72 | KDM4E (0.56) | CYP3A4KDM4EMEN1KMT2AMAPT | |
| SCHEMBL27929423 | 0.71 | KDM4E (0.52) | KDM4EMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL17944028 | 0.71 | TP53 (0.70) | CYP3A4KDM4EMEN1KMT2AMAPT | |
| SCHEMBL27356912 | 0.70 | ESR1 (0.46) | CYP3A4KDM4EMEN1KMT2AMAPT | |
| SCHEMBL12172657 | 0.69 | ESR1 (0.42) | CYP3A4KDM4EMEN1KMT2AMAPT | |
| SCHEMBL10370983 | 0.69 | GPR35 (0.44) | CYP3A4KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| US-9840488-B2 | Carbon monoxide releasing molecules and associated methods | UTAH STATE UNIVERSITY (US) | 2017-12-12 | — | — | US | disclosed |
| WO-2016123141-A1 | CARBON MONOXIDE RELEASING MOLECULES AND ASSOCIATED METHODS | BERREAU LISA M (US) | 2016-08-04 | — | — | WO | disclosed |
| WO-2016123141-A1 | CARBON MONOXIDE RELEASING MOLECULES AND ASSOCIATED METHODS | BERREAU LISA M (US) | 2016-08-04 | — | — | WO | disclosed |
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | UTAH STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | UTAH STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | UTAH STATE UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214955-A1 | Carbon Monoxide Releasing Molecules and Associated Methods | MB, CORO1C, CYCS | CYP3A4 698/4885KDM4E 1691/4885MEN1 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.