SCHEMBL17943458

SCHEMBL17943458

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc(-n5c6ccccc6c6cc7ccccc7cc65)cc4)cc3)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 2/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ HDAC4 P56524 1/20 0.40
▸ KMT2A Q03164 4/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ MAPT P10636 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ RXRA P19793 1/20 0.36
▸ OXTR P30559 1/20 0.36
▸ RAC2 P15153 1/20 0.36
▸ RAC3 P60763 1/20 0.36
▸ CDC42 P60953 1/20 0.36
▸ RAC1 P63000 1/20 0.36
▸ ESR1 P03372 2/20 0.36
▸ ESR2 Q92731 2/20 0.36
▸ AVPR1A P37288 1/20 0.36
▸ PTGER4 P35408 1/20 0.35
▸ HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17943443 1.00 ATM (0.47) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL24152076 1.00 ATM (0.47) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL17943394 1.00 ATM (0.47) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL17991031 0.99 ATM (0.49) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL17245562 0.96 L3MBTL1 (0.50) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL17990514 0.96 L3MBTL1 (0.50) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL24152113 0.95 KDM4E (0.42) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL24152856 0.95 KDM4E (0.42) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL24153999 0.95 KDM4E (0.42) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL24154881 0.95 L3MBTL1 (0.46) ATML3MBTL1KDM4EHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
WO-2021261907-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2021-12-30 — — WO disclosed
WO-2021261977-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2021-12-30 — — WO disclosed
WO-2021261962-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2021-12-30 — — WO disclosed
EP-3551623-B1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-09-22 — — EP disclosed
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-09-17 — — US disclosed
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer LG CHEM, LTD. (KR) 2020-07-14 — — US disclosed
US-20190288222-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2019-09-19 — — US disclosed
WO-2018105888-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2018-06-14 — — WO disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190288222-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ICOSLG, ELAVL1, SOD1 ATM 2115/4885L3MBTL1 111/4885KDM4E 841/4885
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE TPH1, DRD1, CYP1A1 ATM 2503/4885L3MBTL1 2025/4885KDM4E 2126/4885
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer COMT, MAOB, MAOA ATM 641/4885L3MBTL1 1067/4885KDM4E 2523/4885
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE CRY1, CRY2, NR2E3 ATM 1728/4885L3MBTL1 12/4885KDM4E 2742/4885
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer DRD1, TPH1, DRD3 ATM 1444/4885L3MBTL1 1918/4885KDM4E 2285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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