Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | HTR1A | P08908 | 6/20 | 0.67 |
| ▸ | HTR7 | P34969 | 6/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | DRD4 | P21917 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17946603 | 0.82 | CACNA1G (0.72) | CACNA1GTSHRKMT2AGAAHTR1A | |
| SCHEMBL1577875 | 0.82 | KMT2A (0.70) | DRD2CACNA1GTSHRKMT2AGAA | |
| SCHEMBL3060155 | 0.79 | MAPK1 (0.66) | DRD2DRD3CACNA1GTSHRKMT2A | |
| SCHEMBL3056156 | 0.79 | HTR1A (0.68) | DRD2DRD3TSHRKMT2AGAA | |
| SCHEMBL8442719 | 0.78 | GAA (0.61) | DRD2ADRA1ADRD3CACNA1GTSHR | |
| SCHEMBL4005507 | 0.78 | DRD4 (1.00) | DRD2DRD3TSHRKMT2AUSP2 | |
| SCHEMBL9024439 | 0.78 | KMT2A (0.64) | ADRA1ACACNA1GTSHRKMT2AGAA | |
| SCHEMBL15444518 | 0.78 | ALDH1A1 (0.97) | KMT2AMAPK1ALDH1A1MAPT | |
| SCHEMBL8443516 | 0.77 | HTR1A (0.65) | DRD2KMT2AHTR1AHTR7PDE4B | |
| SCHEMBL10864141 | 0.77 | DRD4 (0.72) | DRD2HTR1AHTR7PDE4BDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298051-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2017-10-19 | — | — | US | disclosed |
| US-20170298051-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-3053911-A1 | ADIPONECTIN RECEPTOR-ACTIVATING COMPOUND | The University of Tokyo (JP) | 2016-08-10 | — | — | EP | disclosed |
| US-20160214967-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2016-07-28 | — | — | US | disclosed |
| US-20160214967-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214967-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | ADIPOR1, ADIPOR2, CCKAR | DRD2 1797/4885ADRA1A 35/4885DRD3 2456/4885 |
| US-20170298051-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | ADIPOR1, ADIPOR2, CCKAR | DRD2 1797/4885ADRA1A 35/4885DRD3 2456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.