Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 3/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17961631 | 0.87 | LMNA (0.64) | ALDH1A1KMT2ARAB9ALMNARECQL | |
| SCHEMBL12615015 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KMT2ARAB9ALMNATSHR | |
| SCHEMBL17970866 | 0.83 | ALDH1A1 (0.78) | ALDH1A1KMT2ARAB9ALMNATSHR | |
| SCHEMBL931458 | 0.83 | ALDH1A1 (0.78) | ALDH1A1KMT2ARAB9ALMNATSHR | |
| SCHEMBL17368844 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KMT2ARAB9ALMNARECQL | |
| SCHEMBL5252168 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KMT2ARAB9AHSD11B1MEN1 | |
| SCHEMBL28969725 | 0.79 | PSEN1 (0.62) | ALDH1A1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL17371677 | 0.78 | KMT2A (0.73) | ALDH1A1KMT2ARAB9ATAS2R14MEN1 | |
| SCHEMBL31004048 | 0.77 | ALDH1A1 (0.78) | ALDH1A1KMT2ARAB9ALMNATSHR | |
| SCHEMBL1792200 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KMT2ARAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459385-A | Method for synthesizing 2-phenyl-1- (phenylsulfonyl) aziridine compound | 常州大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-112608269-B | Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen | 山东大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-112608269-A | Method for catalytically synthesizing pyrrolidine by weak interaction of chalcogen | 山东大学 | 2021-04-06 | — | — | CN | disclosed |
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-05-12 | — | — | US | disclosed |
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-05-12 | — | — | US | disclosed |
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-05-12 | — | — | US | disclosed |
| WO-2009146032-A2 | METAL PORPHYRIN CATALYZED OLEFIN AZIRIDINATION WITH SULFONYL AZIDES | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146032-A2 | METAL PORPHYRIN CATALYZED OLEFIN AZIRIDINATION WITH SULFONYL AZIDES | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | PPOX, SOD1, AP1S1 | ALDH1A1 1473/4885KMT2A 3295/4885RAB9A 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.