Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13544391 | 0.81 | NAALAD2 (0.47) | NAALAD2EPHX1TSHRALDH1A1KDM4C | |
| SCHEMBL5607969 | 0.81 | NAALAD2 (0.47) | NAALAD2EPHX1TSHRALDH1A1KDM4C | |
| SCHEMBL25446061 | 0.79 | NAALAD2 (0.45) | NAALAD2EPHX1TSHRALDH1A1KDM4C | |
| SCHEMBL14879626 | 0.79 | NAALAD2 (0.45) | NAALAD2EPHX1TSHRALDH1A1KDM4C | |
| SCHEMBL9978303 | 0.77 | NAALAD2 (0.44) | NAALAD2EPHX1TSHRALDH1A1KDM4C | |
| SCHEMBL24978672 | 0.77 | NAALAD2 (0.53) | NAALAD2EPHX1ALDH1A1PKMTHRB | |
| SCHEMBL8995753 | 0.76 | FPR2 (0.50) | NAALAD2TSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL8995757 | 0.76 | FPR2 (0.50) | NAALAD2TSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL8995750 | 0.76 | FPR2 (0.50) | NAALAD2TSHRALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL2235123 | 0.75 | ALDH1A1 (0.36) | NAALAD2EPHX1TSHRALDH1A1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160221941-A1 | SELENOCYSTINE DERIVATIVES, ALPHA-METHYLSELENOCYSTEINE, ALPHA-METHYLSELENOCYSTEINE DERIVATIVES, AND METHODS OF MAKING AND USING SAME | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221941-A1 | SELENOCYSTINE DERIVATIVES, ALPHA-METHYLSELENOCYSTEINE, ALPHA-METHYLSELENOCYSTEINE DERIVATIVES, AND METHODS OF MAKING AND USING SAME | SCLY, SELENOI, BHMT | NAALAD2 434/4885EPHX1 446/4885TSHR 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.