Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17961090 | 0.94 | CA2 (0.38) | TAS1R3TAS1R1POLBKMT2APTPN1 | |
| SCHEMBL18307152 | 0.94 | CA2 (0.38) | TAS1R3TAS1R1POLBKMT2APTPN1 | |
| SCHEMBL17877818 | 0.94 | CA2 (0.38) | TAS1R3TAS1R1POLBKMT2APTPN1 | |
| SCHEMBL29382956 | 0.94 | CA2 (0.38) | TAS1R3TAS1R1POLBKMT2APTPN1 | |
| SCHEMBL29870167 | 0.82 | TDP1 (0.46) | POLBPTPN1APEX1RECQLBACE1 | |
| SCHEMBL29870166 | 0.82 | TDP1 (0.46) | POLBPTPN1APEX1RECQLBACE1 | |
| SCHEMBL17877817 | 0.81 | OPRM1 (0.41) | POLBPTPN1CTSKAPEX1RECQL | |
| SCHEMBL13425366 | 0.65 | PTPN1 (0.42) | KMT2APTPN1 | |
| SCHEMBL10431871 | 0.65 | HIF1A (0.49) | POLBPTPN1APEX1RECQLACHE | |
| SCHEMBL9634302 | 0.62 | HIF1A (0.52) | PTPN1SMN1; SMN2CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944962-B2 | Clone of xiamenmycin biosynthesis gene cluster and heterologous expression thereof | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2018-04-17 | — | — | US | disclosed |
| US-9944962-B2 | Clone of xiamenmycin biosynthesis gene cluster and heterologous expression thereof | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2018-04-17 | — | — | US | disclosed |
| US-20160222422-A1 | Xiamenmycin biosynthesis gene cluster, application and bacterial strain | UNIV SHANGHAI JIAOTONG (CN) | 2016-08-04 | — | — | US | disclosed |
| US-20160222422-A1 | Xiamenmycin biosynthesis gene cluster, application and bacterial strain | UNIV SHANGHAI JIAOTONG (CN) | 2016-08-04 | — | — | US | disclosed |