Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870166 | 1.00 | TDP1 (0.46) | TDP1BACE1RXRAALOX5ALOX15 | |
| SCHEMBL17877817 | 0.90 | OPRM1 (0.41) | TDP1BACE1PTPN1POLBAPEX1 | |
| SCHEMBL17961090 | 0.82 | CA2 (0.38) | TDP1PTPN1POLB | |
| SCHEMBL17877818 | 0.82 | CA2 (0.38) | TDP1PTPN1POLB | |
| SCHEMBL17974038 | 0.82 | TAS1R3 (0.34) | BACE1PTPN1POLBAPEX1RECQL | |
| SCHEMBL13425366 | 0.79 | PTPN1 (0.42) | RXRAALOX5ALOX15ALOX12PTPN1 | |
| SCHEMBL10431871 | 0.72 | HIF1A (0.49) | TDP1PTPN1POLBAPEX1RECQL | |
| SCHEMBL30195971 | 0.67 | RXRA (0.64) | TDP1RXRAPOLBALDH1A1MAPK1 | |
| SCHEMBL14898029 | 0.67 | RXRA (0.50) | TDP1RXRAALOX5POLBALDH1A1 | |
| SCHEMBL3880185 | 0.67 | RXRA (0.64) | TDP1RXRAPOLBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112940999-B | Streptomyces xiamenensis and method for biologically synthesizing benzopyran and 4-hydroquinoline compounds by Streptomyces xiamenensis | 上海交通大学 | 2022-08-23 | — | — | CN | disclosed |