Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17961090 | 1.00 | CA2 (0.38) | CA2CA1TAS1R3TAS1R1POLB | |
| SCHEMBL29382956 | 1.00 | CA2 (0.38) | CA2CA1TAS1R3TAS1R1POLB | |
| SCHEMBL18307152 | 1.00 | CA2 (0.38) | CA2CA1TAS1R3TAS1R1POLB | |
| SCHEMBL17974038 | 0.94 | TAS1R3 (0.34) | CA2CA1TAS1R3TAS1R1POLB | |
| SCHEMBL29870167 | 0.82 | TDP1 (0.46) | POLBPTPN1TDP1 | |
| SCHEMBL29870166 | 0.82 | TDP1 (0.46) | POLBPTPN1TDP1 | |
| SCHEMBL17877817 | 0.79 | OPRM1 (0.41) | POLBPTPN1TDP1 | |
| SCHEMBL13425366 | 0.66 | PTPN1 (0.42) | KMT2APTPN1 | |
| SCHEMBL10431871 | 0.63 | HIF1A (0.49) | POLBPTPN1TDP1 | |
| SCHEMBL5407656 | 0.61 | TAS1R3 (0.62) | TAS1R3TAS1R1POLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017489-B2 | Method for preparing benzopyran compound and application thereof in treating pulmonary fibrosis | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2018-07-10 | — | — | US | disclosed |
| US-10017489-B2 | Method for preparing benzopyran compound and application thereof in treating pulmonary fibrosis | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2018-07-10 | — | — | US | disclosed |
| US-20160185742-A1 | Method for Preparing Benzopyran Compound and Application thereof in Treating Pulmonary Fibrosis | UNIV SHANGHAI JIAOTONG (CN) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017489-B2 | Method for preparing benzopyran compound and application thereof in treating pulmonary fibrosis | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNC, FIBP | CA2 1701/4885CA1 4423/4885TAS1R3 4851/4885 |
| US-20160185742-A1 | Method for Preparing Benzopyran Compound and Application thereof in Treating Pulmonary Fibrosis | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNC, FIBP | CA2 1701/4885CA1 4423/4885TAS1R3 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.