Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17961090 | 1.00 | CA2 (0.38) | CA2CA1TAS1R3TAS1R1POLB | |
| SCHEMBL29382956 | 1.00 | CA2 (0.38) | CA2CA1TAS1R3TAS1R1POLB | |
| SCHEMBL17877818 | 1.00 | CA2 (0.38) | CA2CA1TAS1R3TAS1R1POLB | |
| SCHEMBL17974038 | 0.94 | TAS1R3 (0.34) | CA2CA1TAS1R3TAS1R1POLB | |
| SCHEMBL29870167 | 0.82 | TDP1 (0.46) | POLBPTPN1TDP1 | |
| SCHEMBL29870166 | 0.82 | TDP1 (0.46) | POLBPTPN1TDP1 | |
| SCHEMBL17877817 | 0.79 | OPRM1 (0.41) | POLBPTPN1TDP1 | |
| SCHEMBL13425366 | 0.66 | PTPN1 (0.42) | KMT2APTPN1 | |
| SCHEMBL10431871 | 0.63 | HIF1A (0.49) | POLBPTPN1TDP1 | |
| SCHEMBL5407656 | 0.61 | TAS1R3 (0.62) | TAS1R3TAS1R1POLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3103873-B1 | BIOSYNTHESIS GENE CLUSTER OF STREPTOMYCES XIAMENENSIS, USE AND BACTERIAL STRAIN | UNIV SHANGHAI JIAOTONG (CN) | 2018-07-11 | — | — | EP | disclosed |
| EP-3103873-A1 | BIOSYNTHESIS GENE CLUSTER OF STREPTOMYCES XIAMENENSIS, PURPOSE, AND BACTERIAL STRAIN | Shanghai Jiao Tong University (CN) | 2016-12-14 | — | — | EP | disclosed |