Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32673266 | 0.88 | ALDH1A1 (0.49) | CES2CES1RECQLMAPK14ALDH1A1 | |
| SCHEMBL2705789 | 0.83 | RECQL (0.62) | CES2CES1BCHERECQLHPGD | |
| SCHEMBL14917063 | 0.78 | MAPT (0.47) | MAPK14ALDH1A1MAPTALOX15 | |
| SCHEMBL3440833 | 0.78 | CES2 (0.74) | CES2CES1BCHEHPGDMAPK14 | |
| SCHEMBL28003970 | 0.76 | ALDH1A1 (0.47) | CES2CES1RECQLMAPK14ALDH1A1 | |
| SCHEMBL3111227 | 0.75 | CES2 (0.63) | CES2CES1BCHEHPGDMAPK14 | |
| SCHEMBL23293839 | 0.73 | IKBKB (0.42) | ALDH1A1GRM2 | |
| SCHEMBL13469240 | 0.73 | CYP3A4 (0.55) | HPGDALDH1A1MAPTSMN1; SMN2GRM2 | |
| SCHEMBL29918078 | 0.73 | CYP3A4 (0.55) | HPGDALDH1A1MAPTSMN1; SMN2GRM2 | |
| SCHEMBL5613020 | 0.73 | CES2 (0.65) | CES2CES1BCHEHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257841-B1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | SHANGHAI DESANO PHARMACEUTICAL CO LTD (CN) | 2020-07-08 | — | — | EP | claimed |
| US-20180029975-A1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | SHANGHAI DESANO PHARMACEUTICAL CO., LTD. (CN) | 2018-02-01 | — | — | US | claimed |
| EP-3257841-A1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | Shanghai Desano Pharmaceutical Co., Ltd. (CN) | 2017-12-20 | — | — | EP | claimed |
| EP-3257841-B1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | SHANGHAI DESANO PHARMACEUTICAL CO LTD (CN) | 2020-07-08 | — | — | EP | disclosed |
| CN-110746312-A | Method for asymmetrically synthesizing efavirenz key intermediate of anti-AIDS drug | 湖北随州双星生物科技有限公司 | 2020-02-04 | — | — | CN | disclosed |
| US-20180029975-A1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | SHANGHAI DESANO PHARMACEUTICAL CO., LTD. (CN) | 2018-02-01 | — | — | US | disclosed |
| US-20180029975-A1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | SHANGHAI DESANO PHARMACEUTICAL CO., LTD. (CN) | 2018-02-01 | — | — | US | disclosed |
| EP-3257841-A1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | Shanghai Desano Pharmaceutical Co., Ltd. (CN) | 2017-12-20 | — | — | EP | disclosed |
| EP-3257841-A1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | Shanghai Desano Pharmaceutical Co., Ltd. (CN) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016127661-A1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | 上海迪赛诺药业有限公司 | 2016-08-18 | — | — | WO | disclosed |
| CN-105330554-A | Synthesis method of chiral cyclopropylacetylenyl tert-alcohol compound | SHANGHAI DESANO PHARMACEUTICAL INVEST CO LTD | 2016-02-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180029975-A1 | SYNTHESIS PROCESS FOR CHIRAL CYCLOPROPYL ETHYNYL TERTIARY ALCOHOL COMPOUND | ADH5, ADH1A, ADH1C | CES2 170/4885CES1 187/4885BCHE 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.