Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979466 | 0.88 | CES2 (0.47) | ALDH1A1MAPTRECQLALOX15CES2 | |
| SCHEMBL28003970 | 0.88 | ALDH1A1 (0.47) | ALDH1A1MAPTRECQLALOX15CES2 | |
| SCHEMBL14917063 | 0.84 | MAPT (0.47) | ALDH1A1MAPTALOX15MAPK14 | |
| SCHEMBL29858361 | 0.82 | RECQL (0.71) | ALDH1A1MAPTRECQLALOX15CES2 | |
| SCHEMBL333224 | 0.82 | RECQL (0.71) | ALDH1A1MAPTRECQLALOX15CES2 | |
| SCHEMBL29515875 | 0.82 | RECQL (0.71) | ALDH1A1MAPTRECQLALOX15CES2 | |
| SCHEMBL1342161 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTRECQLALOX15CES2 | |
| SCHEMBL29963527 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTRECQLALOX15CES2 | |
| SCHEMBL7544330 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTRECQLALOX15CES2 | |
| SCHEMBL2704116 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTRECQLALOX15CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042763-A1 | PERIPHERALLY RESTRICTED GABA POSITIVE ALLOSTERIC MODULATORS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME AND OTHER AILMENTS OF THE PERIPHERAL NERVOUS SYSTEM | UNIV JOHNS HOPKINS (US) | 2026-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042763-A1 | PERIPHERALLY RESTRICTED GABA POSITIVE ALLOSTERIC MODULATORS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME AND OTHER AILMENTS OF THE PERIPHERAL NERVOUS SYSTEM | GABRB2, GABRB3, GABRB1 | ALDH1A1 1600/4885MAPT 2868/4885RECQL 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.